Summaries are clearly marked paraphrases. Citation does not imply endorsement of LifeIP or its proposals.
Established scholarship
A Unified Framework of Five Principles for AI in Society
Luciano Floridi & Josh Cowls
Harvard Data Science Review, 1(1), 2019
Paraphrase: surveys several prominent sets of AI ethics principles and finds substantial convergence around the four classic bioethics principles, adding explicability (intelligibility and accountability) as a fifth that enables the others.
Oxford University Press, first ed. 1979; 8th ed. 2019
Paraphrase: the foundational account of respect for autonomy, non-maleficence, beneficence and justice as mid-level principles for clinical and research ethics.
Paraphrase: maps 84 guideline documents and reports convergence on themes such as transparency, justice and non-maleficence, alongside real divergence in how principles are interpreted and implemented.
Paraphrase: a critique arguing that the medical-ethics analogy is limited for AI, because AI development lacks medicine's shared goals, professional history and accountability mechanisms.
Reviews of guideline documents find recurring themes. Floridi and Cowls group them as:
Beneficence — Promote well-being.
Non-maleficence — Anticipate and reduce harm.
Autonomy — Preserve meaningful human choice.
Justice — Distribute benefits and burdens fairly.
Explicability — Support understanding and accountability.
Disagreement
Whether medical-ethics principles transfer to AI without medicine’s professional accountability (Mittelstadt).
How principles are interpreted and ranked when they conflict (Jobin, Ienca & Vayena).
Whether principles can be translated into concrete, testable engineering requirements.
Agentic AI
Moral reasoning when AI starts to act.
Paraphrased from Prof. Stephanie Dick (Simon Fraser University; co-editor, Harvard Data Science Review), Harvard Data Science Initiative session on ethics and moral reasoning in agentic AI.
From automating labour to automating action
Factories automated physical work and computers automated mental work; agentic AI aims to automate the capacity to decide, initiate and act, which demands judgement and self-regulation.
No ‘ought’ from an ‘is’
Following Hume, moral reasoning always needs a step beyond the facts, taken by principles the data cannot supply. Consequentialism, deontology and virtue ethics give different answers.
Frameworks shape liability
Different ethical frameworks imply different liabilities and customer expectations, and different stakeholders judge an AI's choices differently.
Which humans?
Research by Atari, Xue, Park, Blasi and Henrich finds language-model responses resemble some populations' values far more than others, so a model's built-in ethics is not neutral.
Ethics lives in organizations, not models
Responsibility is enacted across workflows, human oversight, technical constraints, audits, refusal conditions and escalation paths.
Audits as governance
Audits surface how responsibility, risk and harm are allocated by a system in operation.
Questions LifeIP asks of every system
Which steps in a workflow require moral reasoning, and under what circumstances?
What ethical assumptions are our systems already making, and how do we know?
What principles should guide that reasoning, and do they match our stated values?
How are accountability and oversight structured around the agent?
Get involved
How to join the wider bioethics and AI ethics community.
Most professional societies take open individual membership with yearly dues; research labs and journals are joined by contributing work. Terms change, so confirm on each site.
Bioethics
American Society for Bioethics and Humanities (ASBH)
Open to anyone with an interest in healthcare ethics. Yearly dues are based on income, from $75 (under $35,000) to $475. Members can vote, hold office and attend the annual conference.
Open individual membership: $70 (high-income countries), $60 (middle-income), $25 (low-income countries and students), $35 (early-career researchers). Members can register for the World Congress of Bioethics and vote for the board.
MINT Lab (Machine Intelligence and Normative Theory)
Research lab led by Seth Lazar, now a professor at Johns Hopkins University. Engage via its public seminars and publications, or apply for posted PhD and postdoc positions.
AAAI offers open membership for professionals and students, with discounts on conference registration; the AI, Ethics and Society conference accepts open submissions.